"New strategies for the synthesis and functionalization of strained rings"

Abstract: Cyclopropanes are found in numerous biologically active molecules, including natural products, pharmaceuticals and agrochemicals. My group has had a long-standing interest in the chemistry of cyclopropanol derivatives including the development of new methods to functionalize the C–O bond in these compounds. We have been investigating the functionalization of cyclopropane derivatives, through ring-opening reactions to generate metal homoenolates or in Ni-catalyzed cross-coupling reactions. In this presentation, I will highlight our efforts in this area, including new ventures in photocatalysis to access functionalized cyclopropanes.

• This event is part of the Baker Lecture Series