About Bitterroot Bio
Bitterroot Bio is committed to pioneering the emerging field of cardio-immunology, which investigates the interplay between the immune system and cardiovascular health. Our ultimate goal is to provide new hope to those suffering from cardiovascular disease and transform the way these diseases are treated.
Summary
We are seeking a highly driven scientist to join our dynamic research team in Palo Alto. This role will contribute to the growth of Bitteroot’s research portfolio by developing assay strategies to advance the discovery and validation of novel cardio immunology therapies. This position is ideal for a talented, highly motivated and results driven individual who will thrive in a fast-paced, innovative, start-up environment.
Responsibilities:
• Design and execution of in vitro assays to identify and validate novel therapeutics using cell-free and cell based models.
• Develop assays to investigate, potency, selectivity, ADME, and bioactivity of molecules.
• Develop new assays and initiate new experimental approaches to investigate mode of action; Translate these proof-of-concept assays into high-quality, streamlined sensitive protocols
• Participate in troubleshooting of methods with internal partners and/CROs.
• Analyze data and maintain clear laboratory records, protocols, summaries, and reports.
• Prepare and present experimental results to project and team leads and external stakeholders.
Qualifications:
• D. or MSc 3+ years or 7+ relevant experience post bachelor’s degree.
• Proficient in various innovative biophysical, biochemical and/or cellular assay platforms and workflows relevant to in vitro pharmacology (i.e. ELISA, MSD, Luminex, biochemical assays, enzyme kinetics, Western Blot, RNA and protein expression methods, microscopy etc.)
• A highly engaged scientist with the desire to work in a fast-paced, multi-tasking environment, with both a collaborative and goal/results-orientated style.
• Critical thinking with the ability to analyze possibilities and prioritize solutions
Preferred Qualifications:
• Experience with in vivo models and methods would be a plus
• Good understanding of drug development process and relevant assays
• Strong preference for biologics experience in industry environment
• A positive, collaborative attitude with a problem-solving, goal orientated mindset.
Physical Demands & Work Environment
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
To perform this duty the employee must have the ability to sit or stand at and operate a computer terminal and walk or travel within the facility. The employee may occasionally lift and/or move up to 15 pounds.
This position is based in the San Francisco Bay Area, with the ability to commute into the office at least 4 days a week.
For US Based Candidates Only
For this role, the anticipated base pay range is $90,000 - $160,000 a year.
Bitterroot Bio is committed to fair and equitable compensation practices. While our ranges are posted, the exact base pay offered for this role will depend on various factors, including but not limited to the successful candidate's qualifications, skills, experience, location or comparison to other employees already in similar roles. In addition to base salary, our positions are eligible for variable compensation through one of our incentive plans as well as equity compensation based on role and level. Bitterroot Bio also offers a generous healthcare plan, 401k retirement savings plan with a company match, unlimited paid time off, cellphone and internet reimbursement, office snacks, weekly team lunches and fun company culture.
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